At Elle Medical Aesthetics, we use Polynucleotides to treat concerns including fine lines, tired-looking eyes, acne scarring, dull skin and loss of elasticity, creating natural-looking results that continue to improve over time.
What Are Polynucleotides?
Polynucleotides are an injectable regenerative treatment that supports your skin’s natural ability to repair and renew itself. They are made from highly purified DNA fragments which encourage cell regeneration, stimulate collagen and elastin production and improve overall skin quality.
Unlike dermal fillers, Polynucleotides do not add volume or alter the shape of your face. Instead, they focus on improving the health, texture and appearance of your skin, making them an excellent option for patients seeking subtle, natural-looking rejuvenation.
As one of the fastest-growing treatments in aesthetic medicine, Polynucleotides are particularly effective for improving delicate areas such as around the eyes, whilst also treating ageing, damaged or dehydrated skin across the face, neck and décolletage.
What Can Polynucleotides Treat?
Tired-Looking Eyes
Improve the delicate skin around the eyes by reducing crepey texture and creating a brighter, more refreshed appearance.
Fine Lines & Wrinkles
Stimulate collagen production to soften early signs of ageing while improving skin firmness and elasticity.
Acne Scarring
Encourage skin regeneration to improve texture and reduce the appearance of post-acne scarring over time.
Dull & Dehydrated Skin
Restore hydration, improve skin quality and create a healthier, more radiant complexion.
Loss of Skin Elasticity
Strengthen and rejuvenate ageing skin by encouraging natural collagen and elastin production.
Sun-Damaged Skin
Support healthier skin repair and improve overall texture, tone and resilience.
Is This Treatment Right for Me?
Polynucleotides may be an excellent option if you:
- Are concerned about fine lines or early signs of ageing.
- Want healthier-looking skin rather than additional facial volume.
- Have noticed the skin around your eyes becoming thinner or crepey.
- Want to improve skin texture, hydration and overall skin quality.
- Are looking for subtle, natural-looking rejuvenation.
- Prefer treatments that work with your body’s own regenerative processes.
During your consultation, we’ll discuss your skin concerns and recommend whether Polynucleotides are the most appropriate treatment or whether another option may better suit your goals.
Areas That Can Be Treated
Under-Eye Area
A popular treatment for tired-looking eyes, crepey skin and fine lines.
Face
Improve skin quality, hydration, elasticity and overall radiance.
Neck
Reduce signs of ageing and improve skin firmness.
Décolletage
Treat sun damage and improve skin texture.
Hands
Restore healthier-looking skin to ageing hands.
Acne Scarring
Support long-term skin regeneration and smoother skin texture.
Polynucleotides vs Dermal Fillers
Although both treatments are injectable, Polynucleotides and Dermal Fillers work in very different ways.
| Polynucleotides | Dermal Fillers |
| Improve skin quality | Restore lost volume |
| Stimulate collagen production | Add shape and definition |
| Regenerate skin naturally | Provide immediate volume |
| Ideal for skin rejuvenation | Ideal for facial contouring |
| Excellent for the eye area | Commonly used for lips, cheeks and jawline |
Many patients benefit from combining both treatments as part of a personalised facial rejuvenation plan.
Why Choose Elle Medical Aesthetics?
At Elle Medical Aesthetics, every treatment is tailored to you. Our focus is on achieving natural-looking results that enhance your skin while maintaining facial harmony.
- Qualified and experienced aesthetic practitioner
- Personalised treatment plans
- Advanced regenerative skin treatments
- Natural-looking rejuvenation
- Friendly clinic in Chorley, Lancashire


Frequently Asked Questions
No. Polynucleotides do not add volume or change facial contours. They are regenerative treatments that improve skin quality by stimulating the body’s natural repair processes.
Many patients benefit from a course of 2–3 treatments spaced several weeks apart. During your consultation, we’ll recommend the most suitable treatment plan for your skin concerns.
Some improvements may be visible after your first treatment, but the best results develop gradually as collagen production increases over the following weeks
Yes, they are particularly effective for improving skin quality beneath the eyes and can help reduce the appearance of tired-looking eyes, crepey skin and fine lines.
Yes. By stimulating skin regeneration and collagen production, Polynucleotides can help improve skin texture and soften the appearance of acne scarring over time.
Yes. Polynucleotides are often combined with treatments such as Skin Boosters, Microneedling and Dermal Fillers as part of a personalised facial rejuvenation plan.
You may experience temporary redness, swelling or mild bruising following treatment, but these effects usually settle within a few days.
When carried out by a qualified and experienced practitioner, Polynucleotide treatments are considered safe and well tolerated. During your consultation, we’ll assess your suitability and answer any questions before treatment.
Results vary between individuals, but many patients enjoy improvements for several months following a full treatment course. Maintenance treatments can help prolong results.
Most healthy adults are suitable candidates, although treatment may not be recommended during pregnancy, breastfeeding or for certain medical conditions. Suitability will always be assessed during your consultation